Internet Security Research Group (ISRG) is the non-profit entity that operates the Let's Encrypt Certificate Authority. Some policies that apply to Let's Encrypt are ISRG policies, some are specific to Let's Encrypt.
To report private key compromise, certificate misuse, or other types of fraud, compromise, misuse, inappropriate conduct, or any other matter related to certificates, please email cert-prob-reports@letsencrypt.org.